Cancer Usurps Skeletal Muscle as an Energy Repository
نویسندگان
چکیده
منابع مشابه
Cancer usurps skeletal muscle as an energy repository.
Cancer cells produce energy through aerobic glycolysis, but contributions of host tissues to cancer energy metabolism are unclear. In this study, we aimed to elucidate the cancer-host energy production relationship, in particular, between cancer energy production and host muscle. During the development and progression of colorectal cancer, expression of the secreted autophagy-inducing stress pr...
متن کاملTumor and Stem Cell Biology Cancer Usurps Skeletal Muscle as an Energy Repository
Cancer cells produce energy through aerobic glycolysis, but contributions of host tissues to cancer energy metabolism are unclear. In this study, we aimed to elucidate the cancer–host energy production relationship, in particular, between cancer energy production and host muscle. During the development and progression of colorectal cancer, expression of the secreted autophagy-inducing stress pr...
متن کاملGamma interferon as an antifibrosis agent in skeletal muscle.
Muscle injuries are a common problem in sports medicine. Skeletal muscle can regenerate itself, but the process is both slow and incomplete. Previously we and others have used growth factors to improve the regeneration of muscle, but the muscle healing was impeded by scar tissue formation. However, when we blocked the fibrosis process with decorin, an antifibrosis agent, we improved the muscle ...
متن کاملSkeletal muscle: an endocrine organ.
Tropism and efficiency of skeletal muscle depend on the complex balance between anabolic and catabolic factors. This balance gradually deteriorates with aging, leading to an age-related decline in muscle quantity and quality, called sarcopenia: this condition plays a central role in physical and functional impairment in late life. The knowledge of the mechanisms that induce sarcopenia and the a...
متن کاملGlycogen as a fuel for skeletal muscle.
The utilization of glycogen by skeletal muscle was, at one time, one of the central problems of biochemistry. Attention focused on the most dramatic property of the system: the very rapid glycogenolysis that occurs synchronously with muscle contraction. This phenomenon now has a generally accepted explanation : the increase in Ca2+ that induces muscle contraction also activates phosphorylase ki...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer Research
سال: 2013
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-13-1052